I describe two new species of microhylid frogs from the mountains of the central cordillera of western Papua New Guinea. One of these is in the arboreal genus Oreophryne; the other is in the fossorial genus Xenorhina. The Oreophryne is one of the largest members of the genus and is characterized by a ligamentous connection of the procoracoid to the scapula, webbing between the toes, fifth toe equal in length to the third, and a relatively short leg, wide head, long and narrow snout, and small finger discs. The Xenorhina species is among the smallest species of the genus and is distinguished by having a single odontoid spike, discs with circum-marginal grooves on all toes but the first, inflated lores, and a relatively long leg, short and broad head and snout, and features of color pattern. The Oreophryne is known from two localities approximately 30 km apart, and the Xenorhina is known only from its type locality. Both occur in the high mountains of Western Province, Papua New Guinea.